Bleformin A

Bleformin A is a potent BChE inhibitor with an IC50 value of 5.2 μM. Bleformin A is a nature product that could be isolated from Bletilla striata. Bleformin A can be used for research of Alzheimer's disease (AD) [1].

Product Specifications

CAS Number

[1980064-35-4]

UNSPSC

12352005

Target

Cholinesterase (ChE)

Type

Natural Products

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/bleformin-a.html

Solubility

10 mM in DMSO

Smiles

OC(C=C1)=CC=C1CC2=C3C(C(C(OC)=C(OC)C(O)=C4)=C4C=C3)=CC=C2O

Molecular Formula

C23H20O5

Molecular Weight

376.40

References & Citations

[1]Liu Y, et, al. Biological evaluation, molecular modeling and dynamics simulation of phenanthrenes isolated from Bletilla striata as butyrylcholinesterase inhibitors. Sci Rep. 2022 Aug 11;12 (1) :13649.