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AM-5308

Product Specifications

UNSPSC Description

AM-5308 is a potent kinesin KIF18A inhibitor (WO2021211549A1, C13)[1].

Target Antigen

Kinesin; Microtubule/Tubulin

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage;Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/am-5308.html

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

C[C@@H](OCC1)CN1C2=NC(NC(C3=C(C=C(C=C3)NS(CCO)(=O)=O)N4CCC5(CC4)CC5)=O)=CC=C2

Molecular Weight

529.65

References & Citations

[1]Marc Noel PAYTON, et al. Kif18a inhibitors for treatment of neoplastic diseases. WO2021211549A1.

Shipping Conditions

Room Temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-144894/AM-5308-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-144894/AM-5308-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

2410796-89-1

Available Sizes

Curated Selection

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