Hexacyclinol
Hexacyclinol exhibits moderate activity against Gram-positive bacteria and can inhibit oxidant production in yeast polysaccharide-stimulated polymorphonuclear leukocytes (PMNL) at concentrations of 4–40 μg/mL. It suppresses the growth of L-930 and K562 cells with IC50 values of 1.4 μg/mL and 0.4 μg/mL, respectively, and has an IC50 of 10 μg/mL for HeLa cells. Additionally, Hexacyclinol shows antimalarial activity, with an IC50 of 2.4 μg/mL against Plasmodium falciparum.
Product Specifications
CAS Number
903574-41-4
Field of Research
Infectious Disease & Virology
Smiles
C (OC) (C) (C) [C@@H]1[C@@]23[C@@] ([C@@] (O[C@@H]2C=C (C) C) ([C@]4 ([C@@] (C3=O) (O4) [H]) [H]) [H]) ([C@]5 (C (=C1) C (=O) [C@@]6 ([C@] ([C@@H]5O) (O6) [H]) [H]) [H]) [H]
Molecular Formula
C23H28O7
Molecular Weight
416.46
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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