Tauroursocholic Acid sodium salt
Tauroursocholic acid (TUCA) is the taurine-conjugated derivative of ursocholic acid and serves as the 7β-hydroxy epimer of taurocholic acid (TCA) . Unlike TCA, TUCA does not inhibit HMG-CoA reductase or the cytochrome P450 (CYP) isoform CYP7A1, also known as cholesterol 7α-hydroxylase. Elevated bile levels of TUCA are observed in patients with biliary tract cancer compared to those with benign biliary conditions.
Product Specifications
CAS Number
17515-36-5
Smiles
O[C@@H]1[C@@]2 ([H]) [C@@]3 ([H]) [C@@] ([C@@] (CC3) ([H]) [C@H] (C) CCC (NCCS (=O) ([O-]) =O) =O) ([C@H] (C[C@]2 ([H]) [C@@]4 ([C@] (C[C@@H] (CC4) O) ([H]) C1) C) O) C.[Na+]
Molecular Formula
C26H44NNaO7S
Molecular Weight
537.69
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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