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KRA-533

KRA-533 is a potent KRAS agonist. KRA-533 binds to the GTP/GDP binding pocket in the KRAS protein to prevent GTP cleavage, resulting in the accumulation of constitutively active GTP-bound KRAS that triggers both apoptotic and autophagic cell death pathways in cancer cells.

Product Specifications

CAS Number

10161-87-2

Purity

>98% (HPLC)

Solubility

DMSO : 250 mg/mL (795.72 mM; ultraphonic; )

Molecular Formula

C13H16BrNO3

Molecular Weight

314.179

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

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