(Pyr5, N-Me-Phe8, Sar9) -Substance P (5-11)
[Glp5, (Me) Phe8, Sar9] Substance P (5-11) (DiMe-C7) is a Substance P analogue that has approximately the same effects as Substance P on neurokinin 1 receptor (NK1R) in rat brain, but with a much longer duration of action. [Glp5, (Me) Phe8, Sar9] Substance P (5-11) selectively activates dopamine metabolism in the mesencephalon and midbrain cortex of the rat brain. [Glp5, (Me) Phe8, Sar9] Substance P (5-11) also increases motor activity and induces recovery of addictive agent-seeking behavior in rats.
Product Specifications
CAS Number
77128-69-9
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 100 mg/mL (113.63 mM; )
Molecular Formula
C43H61N9O9S
Molecular Weight
880.06
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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