TH6342
TH6342 is a SAMHD1 inhibitor with IC50 of 9.1 μM/11.0 μM/5.8 μM against dGTP/Cl-F-ara-ATP/ara-CTP, respectively. TH6342 engages pre-tetrameric SAMHD1 and deter oligomerization and allosteric activation without occupying nucleotide-binding pockets.
Product Specifications
Purity
0.98
Molecular Formula
C19H16ClN5
Molecular Weight
349.82
Notes
For research use only.
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