Mitapivat hydrochloride
Mitapivat (AG-348) hydrochloride is an orally active and selective allosteric activator of pyruvate kinase R (PK-R) . It enhances the PK-R-catalyzed conversion of phosphoenolpyruvate to pyruvate, thereby promoting the glycolysis pathway, increasing ATP production in red blood cells, and decreasing 2,3-diphosphoglycerate (2,3-DPG) levels. Mitapivat hydrochloride is being investigated for potential use in the study of pyruvate kinase deficiency and other anemia-related disorders.
Product Specifications
CAS Number
2559738-69-9
Field of Research
Metabolism Research
Smiles
Cl.O=C (C1=CC=C (C=C1) NS (=O) (=O) C2=CC=CC3=CC=CN=C32) N4CCN (CC4) CC5CC5
Molecular Formula
C24H27ClN4O3S
Molecular Weight
487.014
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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