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Cath-L-dBET1

Cath-L-dBET1 is a PROTAC degrader targeting BRD4. It has an IC50 value of 2.8 μM in MDA-MB-231 cells. Activated by cathepsin L (Cath-L), Cath-L-dBET1 recruits E3 ubiquitin ligase to degrade BRD4 via the ubiquitin-proteasome system. Hyp-dBET1 is applicable for antitumor research.

Product Specifications

Field of Research

Epigenetics & Chromatin, Pharmacology & Drug Discovery

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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