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RIP1-IN-1

RIP1-IN-1 is an orally bioavailable RIP1 inhibitor with a high binding affinity (Kd: 110 nM) . This compound exhibits significant activity against necroptosis and effectively suppresses necrosome formation by inhibiting the phosphorylation of RIP1, RIP3, and MLKL pathways. RIP1-IN-1 can inhibit necroptosis and is applicable in research on acute liver injury.

Product Specifications

Field of Research

Cell Biology, Signal Transduction

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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