EGFR-IN-155

EGFR-IN-155 (compound 13a) is an EGFR inhibitor with IC50 values of 0.14 nM for EGFRTK and 0.18 nM for EGFRL858R. EGFR-IN-155 suppresses tumor growth, causes cell cycle arrest at the S phase, and induces apoptosis (cell death) .