APD-94
APD-94 is a dual inhibitor targeting tubulin and Bmi-1. It disrupts the normal polymerization of tubulin and suppresses the expression of Bmi-1. This compound induces cell cycle arrest at the G2/M phase and triggers apoptosis, thereby inhibiting cancer cell proliferation. Additionally, APD-94 inhibits the growth of HT29 cell xenograft tumors in NOD/SCID mice and is applicable to colorectal cancer research.
Product Specifications
CAS Number
877810-03-2
Field of Research
Cell Biology, Molecular Biology, Signal Transduction
Smiles
OC=1C=C (OC) C=CC1C2=NC (=NC=C2OC3=CC=CC (OC) =C3) N
Molecular Formula
C18H17N3O4
Molecular Weight
339.345
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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