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JAK3-IN-17

JAK3-IN-17 is an orally active JAK3 inhibitor with an IC50 of 14.56 nM. It demonstrates anti-inflammatory activity by inhibiting the production of IL-2 and IL-6 in a DNCB-induced mouse model of atopic dermatitis.

Product Specifications

Field of Research

Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Smiles

FC1=NC=CC=C1C (C=C2) =CN3C2=NC=C3C4=CC (NC (C=C) =O) =CC=C4

Molecular Formula

C21H15FN4O

Molecular Weight

358.37

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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