JAK3-IN-17
JAK3-IN-17 is an orally active JAK3 inhibitor with an IC50 of 14.56 nM. It demonstrates anti-inflammatory activity by inhibiting the production of IL-2 and IL-6 in a DNCB-induced mouse model of atopic dermatitis.
Product Specifications
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Smiles
FC1=NC=CC=C1C (C=C2) =CN3C2=NC=C3C4=CC (NC (C=C) =O) =CC=C4
Molecular Formula
C21H15FN4O
Molecular Weight
358.37
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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