Si5-N14
Si5-N14 is a key component of siloxane-linked lipid nanoparticles (SiLNP) with properties that enhance vascular repair and exhibit antitumor activity. In transgenic GFP mouse models, Si5-N14 mediates CRISPR-Cas9 editing. In Lewis lung carcinoma (LLC) tumor mouse models, it leads to the knockdown of vascular endothelial growth factor receptor 2 (VEGFR2), producing antitumor effects. Additionally, in mice with virus-induced lung injury, Si5-N14 facilitates the delivery of fibroblast growth factor-2 (FGF-2) mRNA, promoting vascular repair, oxygenation, and improved lung function. Si5-N14 shows potential for research in tumors, pneumonia, and cardiovascular diseases.
Product Specifications
CAS Number
3006860-57-4
Field of Research
Cardiovascular Research, Metabolism Research, Signal Transduction
Smiles
O=C (NCCCCCCCCCCCCCC) CCN (CCC (=O) NCCCCCCCCCCCCCC) CCC[Si] (O[Si] (C) (C) CCCN (CCC (=O) NCCCCCCCCCCCCCC) CCC (=O) NCCCCCCCCCCCCCC) (C) C
Molecular Formula
C78H160N6O5Si2
Molecular Weight
1318.31
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
WT1 (Wilm's Tumor 1) (WT1/857), CF647 conjugate, 0.1mg/mL
