JP-153
JP-153 is an inhibitor of Src-FAK-Paxillin signaling. It suppresses Src-dependent phosphorylation of paxillin (Y118) and subsequent activation of Akt (S473) . JP-153 reduces VEGF-induced migration and proliferation of retinal endothelial cells and is applicable in the study of neovascular eye diseases.
Product Specifications
CAS Number
1802937-26-3
Field of Research
Cardiovascular Research, Signal Transduction
Smiles
O=C1OC (C2=CC (OC) =C (OC) C (OC) =C2) C=3C=CC=4C=CC=CC4C3N1
Molecular Formula
C21H19NO5
Molecular Weight
365.379
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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