3′-Deoxy-3′-fluoroguanosine
3′-Deoxy-3′-fluoroguanosine exhibits antiviral activity against tick-borne encephalitis virus (TBEV), through interaction with NS5B RdRp of HCV, resulting in suppression of viral RNA synthesis by disruption of further extension of the replicating viral RNA[1].
Product Specifications
CAS Number
[123402-21-1]
UNSPSC
12352005
Hazard Statement
H302+H312+H332, H314
Target
DNA/RNA Synthesis; HCV
Type
Reference compound
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/3-deoxy-3-fluoroguanosine.html
Purity
99.29
Solubility
DMSO : 20 mg/mL (ultrasonic)
Smiles
NC(NC1=O)=NC2=C1N=CN2[C@@H]3O[C@H](CO)[C@@H](F)[C@H]3O
Molecular Formula
C10H12FN5O4
Molecular Weight
285.24
Precautions
H302+H312+H332, H314
References & Citations
[1]Eyer L, et al., Broad-Spectrum Antiviral Activity of 3'-Deoxy-3'-Fluoroadenosine against Emerging Flaviviruses. Antimicrob Agents Chemother. 2021 Jan 20;65 (2) :e01522-20.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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