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GLP-1R modulator C5

GLP-1R modulator C5 is an allosteric modulator enhancing GLP-1 binding to GLP-1R via a transmembrane site (EC50 1.59 ± 0.53 μM) .

Product Specifications

CAS Number

421578-93-0

UNSPSC

12352005

Target

GCGR

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/glp-1r-modulator-c5.html

Purity

99.81

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(C1=CC=CC=C1)CC2(C(N(C3=CC=CC=C32)CCC4=CC=CC=C4)=O)O

Molecular Formula

C24H21NO3

Molecular Weight

371.43

References & Citations

[1]Wang J, et al. Allosteric Modulators Enhancing GLP-1 Binding to GLP-1R via a Transmembrane Site. ACS Chem Biol. 2021 Nov 19;16 (11) :2444-2452.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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