Quercetagetin

Quercetagetin (6-Hydroxyquercetin) is a flavonoid[1]. Quercetagetin is a moderately potent and selective, cell-permeable pim-1 kinase inhibitor (IC50, 0.34 μM) [2]. Anti-inflammatory and anticancer properties.

Product Specifications

CAS Number

[90-18-6]

Product Name Alternative

6-Hydroxyquercetin

UNSPSC

12352005

Target

Pim

Type

Natural Products

Related Pathways

JAK/STAT Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/Quercetagetin.html

Purity

99.94

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C1C(O)=C(C2=CC=C(O)C(O)=C2)OC3=CC(O)=C(O)C(O)=C13

Molecular Formula

C15H10O8

Molecular Weight

318.24

References & Citations

[1]Yang X, et al. Isolation and identification of an antioxidant flavonoid compound from citrus-processing by-product. J Sci Food Agric. 2011 Aug 15;91 (10) :1925-7.|[2]Holder S, et al. Characterization of a potent and selective small-molecule inhibitor of the PIM1 kinase. Mol Cancer Ther. 2007 Jan;6 (1) :163-72.|[3]Baek S, et al. Structural and functional analysis of the natural JNK1 inhibitor quercetagetin. J Mol Biol. 2013 Jan 23;425 (2) :411-23.