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Azido-PEG8-Amido-Val-Cit-PAB

Azido-PEG8-Amido-Val-Cit-PAB is a cleavable ADC linker efficiently cleaved by cathepsin B. Since cathepsin B is localized in lysosomes, the ADC payload is released exclusively within cells. The azido group reacts with DBCO, BCN, or other alkyne groups through click chemistry. The PEG spacer enhances water solubility. Reagent grade, intended for research purposes.

Product Specifications

CAS Number

2356229-77-9

Field of Research

Signal Transduction

Smiles

N (C ([C@@H] (NC ([C@@H] (NC (COCC (NCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]) =O) =O) [C@@H] (C) C) =O) CCCNC (N) =O) =O) C1=CC=C (CO) C=C1

Molecular Formula

C40H69N9O15

Molecular Weight

916.027

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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