Mal-amide-PEG8-Val-Cit-PAB-PNP
Mal-amide-PEG8-Val-Cit-PAB-PNP is a cleavable ADC linker comprising a maleimide group, a PEG spacer, a Val-Cit dipeptide, PAB, and a PNP carbonate. The maleimide serves as a thiol-specific covalent connector for labeling cysteine residues in proteins, whereas the PNP group acts as a highly reactive leaving group. The Val-Cit linker is cleaved by cytoplasmic peptidases.
Product Specifications
CAS Number
1964490-09-2
Field of Research
Signal Transduction
Smiles
N (C ([C@@H] (NC ([C@@H] (NC (CCOCCOCCOCCOCCOCCOCCOCCOCCNC (CCN1C (=O) C=CC1=O) =O) =O) C (C) C) =O) CCCNC (N) =O) =O) C2=CC=C (COC (OC3=CC=C (N (=O) =O) C=C3) =O) C=C2
Molecular Formula
C51H74N8O20
Molecular Weight
1119.18
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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