DBCO-PEG2-Val-Cit-PAB-MMAE
DBCO-PEG2-Val-Cit-PAB-MMAE is an ADC linker featuring a DBCO group, a Val-Cit dipeptide, a PAB moiety, and an MMAE payload. The DBCO group serves as a click chemistry handle that can react with azide groups, while the Val-Cit dipeptide is protease-cleavable, enabling the release of the MMAE payload into cells through an elimination mechanism.
Product Specifications
CAS Number
2845934-59-8
Field of Research
Metabolism Research
Smiles
C (CCC (NCCOCCOCCC (N[C@H] (C (N[C@H] (C (NC1=CC=C (COC (N ([C@H] (C (N[C@H] (C (N ([C@H] ([C@@H] (CC (=O) N2[C@] ([C@@H] ([C@H] (C (N[C@@H] ([C@@H] (O) C3=CC=CC=C3) C) =O) C) OC) (CCC2) [H]) OC) [C@H] (CC) C) C) =O) C (C) C) =O) C (C) C) C) =O) C=C1) =O) CCCNC (N) =O) =O) [C@H] (C) C) =O) =O) (=O) N4C=5C (C#CC=6C (C4) =CC=CC6) =CC=CC5
Molecular Formula
C84H120N12O17
Molecular Weight
1569.92
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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