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DBCO-PEG2-Val-Cit-PAB-MMAE

DBCO-PEG2-Val-Cit-PAB-MMAE is an ADC linker featuring a DBCO group, a Val-Cit dipeptide, a PAB moiety, and an MMAE payload. The DBCO group serves as a click chemistry handle that can react with azide groups, while the Val-Cit dipeptide is protease-cleavable, enabling the release of the MMAE payload into cells through an elimination mechanism.

Product Specifications

CAS Number

2845934-59-8

Field of Research

Metabolism Research

Smiles

C (CCC (NCCOCCOCCC (N[C@H] (C (N[C@H] (C (NC1=CC=C (COC (N ([C@H] (C (N[C@H] (C (N ([C@H] ([C@@H] (CC (=O) N2[C@] ([C@@H] ([C@H] (C (N[C@@H] ([C@@H] (O) C3=CC=CC=C3) C) =O) C) OC) (CCC2) [H]) OC) [C@H] (CC) C) C) =O) C (C) C) =O) C (C) C) C) =O) C=C1) =O) CCCNC (N) =O) =O) [C@H] (C) C) =O) =O) (=O) N4C=5C (C#CC=6C (C4) =CC=CC6) =CC=CC5

Molecular Formula

C84H120N12O17

Molecular Weight

1569.92

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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