TNF-α-IN-8
Product Specifications
UNSPSC Description
TNF-α-IN-8 (compound I-42) is a TNF-α inhibitor. TNF-α-IN-8 is an isoindole-imide compound. TNF-α-IN-8 can be used for the research of cancer, heart disease, osteoporosis, inflammatory, allergic and autoimmune diseases[1]. TNF-α-IN-8 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Target Antigen
TNF Receptor
Type
Reference compound
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/tnf-α-in-8.html
Solubility
10 mM in DMSO
Smiles
[N-]=[N+]=NCC(NC1=CC=CC(C(N2C3C(NC(CC3)=O)=O)=O)=C1C2=O)=O
Molecular Weight
356.29
References & Citations
[1]Robarge MJ, et al. ISOINDOLE-IMIDE COMPOUNDS, COMPOSITIONS, AND USES THEREOF. WO/2002/059106. 2002.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-148908/TNF-α-IN-8-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-148908/
Clinical Information
No Development Reported
CAS Number
444287-85-8
Available Sizes
Curated Selection
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