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CbzNH-PEG4-CH2COOH

CbzNH-PEG4-CH2COOH is a PEG linker featuring a carboxylic acid (CO2H) group and a benzyloxycarbonyl (Cbz) protecting group. The hydrophilic PEG spacer enhances the compound's solubility in aqueous media. In the presence of activators such as HATU, the terminal carboxylic acid can react with primary amine groups to form stable amide bonds. The benzyloxycarbonyl protecting group can be removed through hydrogenolysis to yield a free amine.

Product Specifications

CAS Number

1451362-51-8

Smiles

O=C (O) COCCOCCOCCOCCNC (=O) OCC=1C=CC=CC1

Molecular Formula

C18H27NO8

Molecular Weight

385.409

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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