Mal-Cyclohexyl-PEG3-Biotin
Mal-Cyclohexyl-PEG3-Biotin is a PEG linker that includes a maleimide moiety and a biotin group. The maleimide specifically reacts with thiols at a pH between 6.5 and 7.5, forming a stable thioether bond. Biotinylation can occur with amine molecules in the presence of activators like EDC or HATU. The PEG linkage, attached to biotin, creates an extended spacer arm, facilitating biotin's access to protein binding sites. Additionally, the PEG component enhances the solubility of the biotin-PEG conjugate significantly.
Product Specifications
CAS Number
2639395-45-0
Field of Research
Cell Biology
Smiles
C (CCCC (NCCOCCOCCOCCNC (=O) C1CCC (CN2C (=O) C=CC2=O) CC1) =O) [C@H]3[C@@]4 ([C@] (CS3) (NC (=O) N4) [H]) [H]
Molecular Formula
C30H47N5O8S
Molecular Weight
637.788
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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