[Deamino-Pen1, Val4, D-Arg8]-vasopressin

[Deamino-Pen1, Val4, D-Arg8]-vasopressin (AVP-A) is an arginine-vasopressin (AVP) antagonist. AVP-A can significantly lower plasma aldosterone concentration in rats. AVP-A can be used for the research of the growth and steroidogenic capacity of rat adrenal zona glomerulosa[1].

Product Specifications

CAS Number

[64158-84-5]

UNSPSC

12352209

Hazard Statement

H332

Target

Vasopressin Receptor

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/deamino-pen1-val4-d-arg8-vasopressin.html

Solubility

10 mM in DMSO

Smiles

O=C(N[C@@H](C(C)C)C1=O)[C@@H](NC([C@@H](NC(CC(C)(C)SSC[C@H](NC([C@H](CC(N)=O)N1)=O)C(N2[C@@H](CCC2)C(N[C@H](CCCNC(N)=N)C(NCC(N)=O)=O)=O)=O)=O)CC3=CC=C(O)C=C3)=O)CC4=CC=CC=C4

Molecular Formula

C48H69N13O11S2

Molecular Weight

1068.27

Precautions

P261-P271-P304+P340

References & Citations

[1]Mazzocchi G, et al. Evidence that endogenous arginine-vasopressin (AVP) is involved in the maintenance of the growth and steroidogenic capacity of rat adrenal zona glomerulosa. J Steroid Biochem Mol Biol. 1993 Apr;45 (4) :251-6.