Aβ42-IN-2
Aβ42-IN-2 (compound example 36) is a γ-secretase modulator. Aβ42-IN-2 has an IC50 of 6.5 nM for Αβ42. Aβ42-IN-2 can be used for the research of Alzheimer's disease[1].
Product Specifications
CAS Number
1914989-80-2
UNSPSC
12352005
Target
γ-secretase
Type
Reference compound
Related Pathways
Neuronal Signaling; Stem Cell/Wnt
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/aβ42-in-2.html
Purity
98.00
Solubility
DMSO : 20 mg/mL (ultrasonic)
Smiles
CC1=CC(C2=NC(OC)=C(N3C=C(C)N=C3)C=C2)=NN=C1N[C@H](C4=CC=C(OC)C=C4)C
Molecular Formula
C24H26N6O2
Molecular Weight
430.50
References & Citations
[1]Steven L. Wagner, et al. Potent gamma-secretase modulators. WO2016070107A1.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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