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Aβ42-IN-2

Aβ42-IN-2 (compound example 36) is a γ-secretase modulator. Aβ42-IN-2 has an IC50 of 6.5 nM for Αβ42. Aβ42-IN-2 can be used for the research of Alzheimer's disease[1].

Product Specifications

CAS Number

1914989-80-2

UNSPSC

12352005

Target

γ-secretase

Type

Reference compound

Related Pathways

Neuronal Signaling; Stem Cell/Wnt

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/aβ42-in-2.html

Purity

98.00

Solubility

DMSO : 20 mg/mL (ultrasonic)

Smiles

CC1=CC(C2=NC(OC)=C(N3C=C(C)N=C3)C=C2)=NN=C1N[C@H](C4=CC=C(OC)C=C4)C

Molecular Formula

C24H26N6O2

Molecular Weight

430.50

References & Citations

[1]Steven L. Wagner, et al. Potent gamma-secretase modulators. WO2016070107A1.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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