Purified Anti-Human CD105 Antibody[SN6]
Product Specifications
Background
Endoglin (CD105) is a 90 kDa type I transmembrane glycoprotein of the zona pellucida (ZP) family of proteins (1-3) . Endoglin and Betaglycan/T beta RIII are type III receptors for TGF beta superfamily ligands, sharing 71% aa identity in the transmembrane (TM) and cytoplasmic domains. Endoglin is highly expressed on proliferating vascular endothelial cells, chondrocytes, and syncytiotrophoblasts of term placenta, with lower amounts on hematopoietic, mesenchymal and neural crest stem cells, activated monocytes, and lymphoid and myeloid leukemic cells.
Abbreviation
CD105
Gene ID
2022
UniProt
P17813
Host
Mouse
Reactivity
Human
Immunogen
Recombinant Human CD105 protein
Target
HHT; RP11 228B; Osler Rendu Weber syndrome; END; HHT1; ORW1; CD105; ENG; endoglin; AI528660; AI662476; CD 105; CD105 antigen; EGLN; FLJ41744; ORW; Osler Rendu Weber syndrome 1; RP11 228B15.2; S-endoglin; SN6; AI528660; AI662476; CD 105; CD105; CD105 antigen; EGLN; END; Endoglin; Eng; FLJ41744; HHT1; ORW; ORW1; Osler Rendu Weber syndrome 1; RP11 228B15.2; S-endoglin; SN6; ENG; END
Clonality
Monoclonal
Clone
SN6
Conjugation
Unconjugated
Applications
FCM
Field of Research
Immunology; Stem Cells; Cancer; Cardiovascular
Purification
>98%, Protein A/G purified
Concentration
≥ 1 mg/mL
Dilution
66
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Isotype
Mouse IgG1, κ
Available Sizes
Curated Selection
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