SARS-CoV-2 Mpro-IN-29
Product Specifications
UNSPSC Description
SARS-CoV-2 Mpro-IN-29 (Compound 7) is an inhibitor of the SARS-CoV-2 main protease (Mpro) with an IC50 of 310 nM and an EC50 of 0.5 μM in Vero cells. SARS-CoV-2 Mpro-IN-29 binds to the active site of Mpro, blocking the cleavage of viral polyproteins, showing significant antiviral activity and enhanced metabolic function. SARS-CoV-2 Mpro-IN-29 holds potential for research on SARS-CoV-2 antiviral agents[1].
Target Antigen
SARS-CoV; Virus Protease
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/sars-cov-2-mpro-in-29.html
Smiles
O=C([C@@H](NC(C1=CC2=C(C=CC=C2OC)N1)=O)CC(C)C)N[C@@H](CC3=CSC=N3)C(S(=O)(O[Na])=O)(O)[H]
Molecular Weight
546.59
References & Citations
[1]Feys JR, et al. Peptide Aldehydes Incorporating Thiazol-4-yl Alanine Are Potent In Vitro Inhibitors of SARS-CoV-2 Main Protease. ACS Med Chem Lett. 2024 Nov 3;15(11):2046-2052.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-159911/SARS-CoV-2-Mpro-IN-29-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-159911/
Clinical Information
No Development Reported
Curated Selection
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