Clesitamig
Clesitamig is a DLL3/CD3/CD137 trispecific T cell engager, consisting of two CD3/CD137 dual-specific antigen-binding fragments (Fabs) and one additional DLL3 antigen-binding fragment (Fab) . Clesitamig exhibits potent antitumor activity and can be used in research on tumors such as small cell lung cancer[1].
Product Specifications
CAS Number
[2930861-48-4]
Product Name Alternative
ALPS-12; RG-6524; RO 7616789
UNSPSC
12352203
Target
CD3
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/clesitamig.html
Purity
96
Smiles
[Clesitamig]
Molecular Weight
(195.836 kDa)
References & Citations
[1]Mikami H, et al. A DLL3/CD3/CD137 trispecific T cell engager shows potent antitumor activity in small cell lung cancer models. Cancer Research, 2023, 83 (7_Supplement) : 1872-1872.
Shipping Conditions
Dry Ice
Storage Conditions
-80°C
Scientific Category
Inhibitory Antibodies
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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