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R-82150

R-82150 (TIBO-R 82150) is an HIV-1 reverse transcriptase inhibitor that blocks the reverse transcription of viral RNA by binding to the non-substrate binding site of reverse transcriptase, thereby inhibiting viral replication. R-82150 does not inhibit the replication of HIV-2, other RNA viruses, and DNA viruses[1].

Product Specifications

CAS Number

[126320-77-2]

Product Name Alternative

TIBO-R 82150

UNSPSC

12352005

Target

HIV; Reverse Transcriptase

Type

Reference compound

Related Pathways

Anti-infection

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/r-82150.html

Smiles

S=C1NC2=C(N1C[C@H](C)N(C/C=C(C)\C)C3)C3=CC=C2

Molecular Formula

C16H21N3S

Molecular Weight

287.42

References & Citations

[1]Parker K A, et al. A four-step synthesis of TIBO R82150[J]. The Journal of Organic Chemistry, 1991, 56 (15) : 4600-4601.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 1

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