R-82150
R-82150 (TIBO-R 82150) is an HIV-1 reverse transcriptase inhibitor that blocks the reverse transcription of viral RNA by binding to the non-substrate binding site of reverse transcriptase, thereby inhibiting viral replication. R-82150 does not inhibit the replication of HIV-2, other RNA viruses, and DNA viruses[1].
Product Specifications
CAS Number
[126320-77-2]
Product Name Alternative
TIBO-R 82150
UNSPSC
12352005
Target
HIV; Reverse Transcriptase
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/r-82150.html
Smiles
S=C1NC2=C(N1C[C@H](C)N(C/C=C(C)\C)C3)C3=CC=C2
Molecular Formula
C16H21N3S
Molecular Weight
287.42
References & Citations
[1]Parker K A, et al. A four-step synthesis of TIBO R82150[J]. The Journal of Organic Chemistry, 1991, 56 (15) : 4600-4601.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
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