Yadanziolide A

Yadanziolide A, isolated from the cultivated dry seeds of Brucea javanica, has strong antiviral activities with IC50 of 5.5 μM against tobacco mosaic virus. Yadanziolide A shows significant antitumor effects[1][2].

Product Specifications

CAS Number

[95258-14-3]

UNSPSC

12352005

Target

TMV

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/yadanziolide-a.html

Purity

99.42

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O[C@@]1([C@H]2O)[C@@]34[C@@]([C@@H](O)[C@H](O)[C@]1(OC4)CO)([H])[C@]([C@@](C(C)=CC5=O)([H])C[C@@]3([H])OC2=O)([C@@H]5O)C

Molecular Formula

C20H26O10

Molecular Weight

426.41

References & Citations

[1]Yan XH, et al. Anti-tobacco mosaic virus (TMV) Quassinoids from Brucea javanica (L.) Merr. J Agric Food Chem. 2010 Feb 10;58 (3) :1572-7.|[2]Liu JQ, et al. One new pregnane glycoside from the seeds of cultivated Brucea javanica. Arch Pharm Res. 2011 Aug;34 (8) :1297-300.