Raxatrigine
Product Specifications
Product Name Alternative
Vixotrigine; GSK-1014802; CNV1014802
UNSPSC Description
Raxatrigine (GSK-1014802) is a novel small molecule state-dependent sodium channel blocker; Nav1.7 sodium channel inhibitor.
Target Antigen
Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/CNV1014802.html
Purity
99.85
Solubility
DMSO : 83 mg/mL (ultrasonic;warming)
Smiles
O=C([C@H]1N[C@@H](C2=CC=C(OCC3=CC=CC=C3F)C=C2)CC1)N
Molecular Weight
314.35
References & Citations
[1]Large CH, et al. The efficacy of sodium channel blockers to prevent phencyclidine-induced cognitive dysfunction in the rat: potential for novel treatments for schizophrenia. J Pharmacol Exp Ther. 2011 Jul;338(1):100-13.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-12796/Raxatrigine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-12796/Raxatrigine-SDS-MedChemExpress.pdf
Clinical Information
Phase 2
CAS Number
934240-30-9
Available Sizes
Curated Selection
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