BPN 0026709
BPN 0026709 (MT-228) is a selective, blood-brain barrier-permeable non-muscle myosin II inhibitor. BPN 0026709 demonstrates enhanced tolerability by preferentially targeting NMIIB (KI = 1.5 μM) over CMII (KI = 17 μM), with SmMll MD sharing 83.6% sequence identity with NMllB. BPN 0026709 exhibits sustained efficacy in animal models of stimulant use disorder.
Product Specifications
CAS Number
2404652-24-8
Product Name Alternative
BPN0026709
Field of Research
Signal Transduction
Purity
99.53% (May vary between batches)
Smiles
O[C@]12C (N (CC1) C=3C=C (OC) N=CC3) =NC=4C (C2=O) =CC (C) =C (C) C4
Molecular Formula
C19H19N3O3
Molecular Weight
337.37
Storage Conditions
-20°C
Notes
For research use only.
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