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BPN 0026709

BPN 0026709 (MT-228) is a selective, blood-brain barrier-permeable non-muscle myosin II inhibitor. BPN 0026709 demonstrates enhanced tolerability by preferentially targeting NMIIB (KI = 1.5 μM) over CMII (KI = 17 μM), with SmMll MD sharing 83.6% sequence identity with NMllB. BPN 0026709 exhibits sustained efficacy in animal models of stimulant use disorder.

Product Specifications

CAS Number

2404652-24-8

Product Name Alternative

BPN0026709

Field of Research

Signal Transduction

Purity

99.53% (May vary between batches)

Smiles

O[C@]12C (N (CC1) C=3C=C (OC) N=CC3) =NC=4C (C2=O) =CC (C) =C (C) C4

Molecular Formula

C19H19N3O3

Molecular Weight

337.37

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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