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PKMYT1-IN-8

PKMYT1-IN-8 (Compound 137) is a potent, nanomolar-range PKMYT1 inhibitor (IC50 = 9 nM) with additional micromolar activity against several EPH receptors and KIT. It demonstrates anti-proliferative activity in OVCAR3 cancer cells (GI50 = 2.02 μM), supporting its use in cell-based assays for oncology research, particularly in studying cell cycle regulation and kinase signaling pathways.

Product Specifications

CAS Number

3065631-84-4

Field of Research

Cell Biology, Signal Transduction

Smiles

CC1=C (C (=C (C=C1) O) C) N2C (=C (C3=C (N=C (N=C32) C) C (F) (F) F) C (=O) N) N

Molecular Formula

C17H16F3N5O2

Molecular Weight

379.336

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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