Bfl-1-IN-6
Bfl-1-IN-6 (Compound 20) is a potent, orally bioavailable BFL1 inhibitor with a 19 nM IC50. It stabilizes BFL1 protein, induces caspase-3 cleavage, and exhibits in vivo antitumor efficacy in mouse models, supporting its use in cancer research targeting apoptosis pathways.
Product Specifications
CAS Number
3106363-91-8
Field of Research
Cell Biology, Protein Biochemistry
Smiles
C[C@@H] (C1=CC=C (C=C1) Cl) N (C2=CC (=C (C=C2) O[C@@H]3CC[C@H] (C3) N) F) C (=O) C=C
Molecular Formula
C22H24ClFN2O2
Molecular Weight
402.89
Storage Conditions
-20°C
Notes
For research use only.
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