CDK2/9-IN-1
CDK2/9-IN-1 (compound 20a) is a potent, orally bioavailable dual inhibitor of CDK2 (IC50=4 nM) and CDK9 (IC50=9 nM) . It demonstrates antitumor activity by inducing G2/M phase arrest and apoptosis in cancer cells, making it a valuable chemical probe for oncology research in both cellular and animal models.
Product Specifications
CAS Number
2222285-23-4
Field of Research
Cell Biology, Epigenetics & Chromatin
Smiles
O=S (=O) (N) C1=CC=C (C=C1) NC2=NC=C (C (=N2) NC3=NC=CS3) C
Molecular Formula
C14H14N6O2S2
Molecular Weight
362.43
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6185919-01 0.1 mL
RAX (Retina and anterior Neural fold Homeobox, MCOP3, RX) (PE)
Sign In for Pricing
View Details MBS6185919-02 5x 0.1 mL
RAX (Retina and anterior Neural fold Homeobox, MCOP3, RX) (PE)
Sign In for Pricing
View Details T273a 1 Each
Oral cavity cancer with normal tissue array, including TNM/Stage（AJCC 8th edition) and pathology grade, 6 cases/12 cores (core size 1.5mm）
Sign In for Pricing
View Details K0827705 3x 1.0 µg
GAB3 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)
Sign In for Pricing
View Details