CDK2/9-IN-1
CDK2/9-IN-1 (compound 20a) is a potent, orally bioavailable dual inhibitor of CDK2 (IC50=4 nM) and CDK9 (IC50=9 nM) . It demonstrates antitumor activity by inducing G2/M phase arrest and apoptosis in cancer cells, making it a valuable chemical probe for oncology research in both cellular and animal models.
Product Specifications
CAS Number
2222285-23-4
Field of Research
Cell Biology, Epigenetics & Chromatin
Smiles
O=S (=O) (N) C1=CC=C (C=C1) NC2=NC=C (C (=N2) NC3=NC=CS3) C
Molecular Formula
C14H14N6O2S2
Molecular Weight
362.43
Storage Conditions
-20°C
Notes
For research use only.
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