S-N6-Methyladenosylhomocysteine
S-N6-Methyladenosylhomocysteine is a potent and selective DOT1L histone methyltransferase inhibitor (IC50 = 0.29 μM) . This mechanism makes it a valuable chemical probe for epigenetic research, particularly in studies of MLL-rearranged leukemias in both cellular and biochemical assays.
Product Specifications
CAS Number
53228-06-1
Field of Research
Epigenetics & Chromatin
Smiles
O[C@H]1[C@H] (N2C=3C (N=C2) =C (NC) N=CN3) O[C@H] (CSCC[C@@H] (C (O) =O) N) [C@H]1O
Molecular Formula
C15H22N6O5S
Molecular Weight
398.437
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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