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UCB9386

UCB9386 is a potent, brain-penetrant small molecule inhibitor selectively targeting Nuak1 (pIC50 10.1), with additional activity against Nuak2 and Kak2. This tool compound is used in vitro and in vivo to investigate the roles of AMPK-related kinases in neurological diseases and cancer biology.

Product Specifications

CAS Number

3096082-93-5

Field of Research

Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Smiles

C[C@H] (C1=CC=CC=C1) N2C3=CC (=NC=C3N=C (C2=O) N4CC5 (C4) CN (C5) C) C6=CN=C7N6N=CC=C7

Molecular Formula

C27H26N8O

Molecular Weight

478.548

Storage Conditions

-20°C

Notes

For research use only.

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