UCB9386
UCB9386 is a potent, brain-penetrant small molecule inhibitor selectively targeting Nuak1 (pIC50 10.1), with additional activity against Nuak2 and Kak2. This tool compound is used in vitro and in vivo to investigate the roles of AMPK-related kinases in neurological diseases and cancer biology.
Product Specifications
CAS Number
3096082-93-5
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Smiles
C[C@H] (C1=CC=CC=C1) N2C3=CC (=NC=C3N=C (C2=O) N4CC5 (C4) CN (C5) C) C6=CN=C7N6N=CC=C7
Molecular Formula
C27H26N8O
Molecular Weight
478.548
Storage Conditions
-20°C
Notes
For research use only.
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