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NA-17

NA-17 is a naphthalimide-based small molecule with selective antitumor activity, particularly in non-small cell lung cancer (NSCLC) research. It induces p53-dependent G1 phase cell cycle arrest and apoptosis by promoting active p53 accumulation in mitochondria and nuclei, while showing reduced toxicity in normal cell lines like HL-7702 and WI-38 in vitro.

Product Specifications

CAS Number

1708948-28-0

Field of Research

Cell Biology

Smiles

O=C1C2=CC=CC=3C (=CC=C (C (=O) N1CCC4=CC=C5OCOC5=C4) C23) NCCCN (C) C

Molecular Formula

C26H27N3O4

Molecular Weight

445.51

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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