MAT2A-IN-18
MAT2A-IN-18 (Compound 15) is a potent small molecule inhibitor of methionine adenosyltransferase 2A (MAT2A), exhibiting an IC50 value ≤ 50 nM. This compound is a valuable research tool for investigating methionine metabolism in cancers, such as MTAP-deleted tumors, in both cellular and animal models.
Product Specifications
CAS Number
2923986-27-8
Field of Research
Epigenetics & Chromatin, Signal Transduction
Smiles
O=C1N=C (NCC#C) C=2C=CC (Cl) =CC2N1C3=CC=CN=C3C
Molecular Formula
C17H13ClN4O
Molecular Weight
324.764
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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