3-AP-Me
3-AP-Me, a dimethylated derivative of the ribonucleotide reductase inhibitor 3-AP, induces apoptosis by activating ER stress through eIF2α phosphorylation and upregulating ATF4/ATF6. It also activates JNK/p38 kinases and XBP1 splicing. This compound is used in cancer research for studying stress pathways in vitro and in vivo.
Product Specifications
CAS Number
1184391-57-8
Field of Research
Cell Biology, Signal Transduction
Smiles
S=C (NN=CC1=NC=CC=C1N) N (C) C
Molecular Formula
C9H13N5S
Molecular Weight
223.298
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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