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NF-κB/MAPK-IN-2

NF-κB/MAPK-IN-2 is a dual-pathway inhibitor that suppresses LPS-induced pro-inflammatory signaling by reducing phosphorylation of key proteins (p65, IκB, p38, JNK, ERK) and cytokine release (TNF-α, IL-6) . It has demonstrated utility in cellular models of inflammation and shows research potential for investigating septic shock mechanisms.

Product Specifications

CAS Number

3070509-60-0

Field of Research

Signal Transduction

Smiles

CCOC (=O) C1=NOC2=C1C[C@]3 ([C@H] ([C@]2 (C) COC (=O) CCC (=O) N4CCOCC4) CC[C@@]5 ([C@@H]3CC=C6[C@]5 (CC[C@@]7 ([C@H]6CC (CC7) (C) C) C (=O) OCC8=CC=CC=C8) C) C) C

Molecular Formula

C49H66N2O9

Molecular Weight

827.056

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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