PFM046
PFM046 is a potent dual LXRα/β antagonist (IC50: 2.04 μM and 1.58 μM, respectively) . It modulates lipid metabolism genes by downregulating SCD1 and FASN while upregulating ABCA1, and has shown antitumor efficacy in mouse models, supporting its use in oncology and metabolic disease research.
Product Specifications
CAS Number
3053859-57-4
Field of Research
Metabolism Research
Smiles
C[C@@]12[C@] ([C@]3 ([C@] (CC1) ([C@]4 (C) C (=CC3) C[C@@H] (O) CC4) [H]) [H]) (CC[C@@]2 ([C@@H] ([C@H] (CC5=CC=CC=C5) O) C) [H]) [H]
Molecular Formula
C29H42O2
Molecular Weight
422.643
Storage Conditions
-20°C
Notes
For research use only.
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